Searchable abstracts of presentations at key conferences in endocrinology

ea0094p168 | Adrenal and Cardiovascular | SFEBES2023

Developing a methodology to measure post-mortem hair hormone concentration to investigate causes of unexplained stillbirth – assessing cortisol, aldosterone, 17-hydoxyprogesterone and total bile acids

Ball Mia , Manna Luiza , Ovadia Caroline

Background: 3.8 per 1000 UK babies are stillborn, a large proportion of which are “unexplained”; aberrations in adrenal hormones and bile acids are possible contributors. In this study, we aimed to develop methodologies for simple laboratory measurement of adrenal hormone and bile acid concentrations that can be applied to postnatal samples from stillborn babies, using hair as a relatively stable medium, reflective of retrospective fetal hormone leve...